Measurement signal quality assessment on all available and new signals of multi-GNSS (GPS, GLONASS, Galileo, BDS, and QZSS) with real data

Global Navigation Satellite Systems (GNSS) Carrier Phase (CP)-based high-precision positioning techniques have been widely used in geodesy, attitude determination, engineering survey and agricultural applications. With the modernisation of GNSS, multi-constellation and multi-frequency data processing is one of the foci of current GNSS research. The GNSS development authorities have better designs for the new signals, which are aimed for fast acquisition for civil users, less susceptible to interference and multipath, and having lower measurement noise. However, how good are the new signals in practice? The aim of this paper is to provide an early assessment of the newly available signals as well as assessment of the other currently available signals. The signal quality of the multi-GNSS (GPS, GLONASS, Galileo, BDS and QZSS) is assessed by looking at their zero-baseline Double Difference (DD) CP residuals. The impacts of multi-GNSS multi-frequency signals on single-epoch positioning are investigated in terms of accuracy, precision and fixed solution availability with known short baselines

Indoor multipath effect study on the Locata system

GNSS has become one of the most wide- spread measurement technologies, allowing cm-level positioning accuracy using RTK or Network RTK. Unfortunately, the system’s major drawbacks are the requirement for a clear view of the sky and accu- racy dependent on the geometric distribution of the satellites, not only varying throughout the day but also prone to location specific problems. With wide- spread utilisation of GNSS for monitoring of man- made structures and other civil engineering tasks, such shortcomings can be critical. One of possible solution is the deployment of a sup- porting system, such as Locata – a terrestrial posi- tioning technology, which mitigates the need for a clear view of the sky and provides system integrity control. This paper, part of the proposed integration feasibil- ity study, presents Locata performance indoors, its capacity and mitigation methods

In vivo interaction between CDKA and eIF4A: a possible mechanism linking translation and cell proliferation

AbstractIn a proteomics-based screen for proteins interacting with cyclin-dependent protein kinase (CDK), we have identified a novel CDK complex containing the eukaryotic translation initiation factor, eIF4A. Reciprocal immunoprecipitations using antibodies against eIF4A indicate that the interaction is specific. The CDKA–eIF4A complex is abundant in actively proliferating and growing cells but is absent from cells that have ceased dividing. The CDKA–eIF4A complex contains kinase activity that is sensitive to the CDK-specific inhibitor roscovitine. This interaction points to a possible molecular mechanism linking cell proliferation with translational control

Deflection characterisation of rotary systems using a ground-based radar

In the last two decades, an increase in large rotary machines/systems has been witnessed. To ensure safe operation of these systems especially due to extreme stress caused by centrifugal forces as well as the wind or water loadings, regular structural health monitoring (SHM) of the unbalanced parameters, particularly at the blade tips is necessary. For this, the use of non-contact sensors provides the most appropriate approach; however, millimetric out-of-plane deflection monitoring using non-contact sensors at distances >1 m has not been comprehensively addressed for rotary systems, like wind turbines. This study presents a modelling environment to simulate radar returns to analyse rotary systems. Employing Sammon mapping as a dimensionality reduction procedure in conjunction with 2D visualisation, the study demonstrates the characterisation of dynamic deflection parameters using a fast, portable ground-based interferometric radar (GBR). Comparisons between the GBR results with those of a Leica AR20 GPS indicate a divergence ±12.79 mm. The study utilises SHM framework to acquire, normalise, extract, and validate GBR signals within an SHM framework for structures under test or for deflection validation of the new system. Further, it contributes to the non-contact structural fatigue damage detection during design, testing, and operating stages of rotary structures blade tips

Damage detection under temperature conditions using PCA – an application to the Z24 Bridge

Vibration properties of civil structures, which are commonly analysed for damage detection, are affected by changing environmental and operational conditions, and most notably are subjected to bilinear effects from changing ambient temperature conditions. Therefore, damage detection in structures during the past decade has focused on eliminating the effects of these changing environments that affect the vibration properties of the structures. Several methods have been proposed in the literature to tackle the non-linear effects from changing environments. However, these methods can only analyse systems (e.g. natural frequency–environmental and operational system) that have an incremental change in relationship; they cannot model the bilinear effects from the changing temperature conditions, which may lead to false alerts. Hence, a damage detection method is proposed in this paper to tackle the piecewise effects from changing temperature conditions. The method makes use of a Gaussian mixture model to separate the different effects acting on the structures and uses principal component analysis for data processing. The method is applied to the Z24 Bridge, in Switzerland, which was subjected to bilinear effects from changing temperature conditions. The results obtained demonstrate that the proposed method successfully takes into account the piecewise effects to indicate the presence of damage

Using satellites to monitor Severn Bridge structure, UK

The Severn Bridge is a large UK suspension bridge. In 2010, a series of field surveys was commissioned to monitor the magnitude and frequencies of the bridge’s movements, through attaching nine dual-frequency survey grade global navigation satellite system receivers on the bridge and two reference satellite receivers adjacent to the structure. The satellite antenna locations and configuration allow the movements of the north cable to be analysed at four locations, as well as the differential movements of the two suspension cables to each other. In addition, this configuration allows the movements of the tops of the towers to be compared to the cables’ movements, as well as with each other. All in all, this allowed the relative movements of the various locations on the bridge’s suspension cables and tower tops to be compared to each other, at a rate of up to 20 Hz. Overall, some 3 days of raw code and carrier phase satellite data were gathered. During these sessions, normal traffic loading was experienced. This paper describes the survey, presents a selection of the key results and draws conclusions about the effective use of satellite positioning systems to enhance structural health monitoring.The Highways Agency, Severn River Crossing plc and Mott MacDonal

Satellite mapping in cities and below cities: how good is it now?

Global navigation satellite systems (GNSS) have existed since the launch of the US global positioning system constellation in 1978. There is an increasing need for better maps in the digital age, particularly for buried utilities. One of the most convenient methods for creating accurate maps is the use of navigation satellites for positioning. However, built-up urban areas are not ideal for the use of this positioning technology. This paper provides an update on the situation regarding GNSS and assesses how new satellites and signals are contributing to better positioning availability by carrying out a test in a controlled environment. The results show that using combined satellite systems improves availability in urban canyons in some cases, but not in all scenarios. In addition, pipeline mapping technology has been tested and been shown to be an effective means of mapping pipes deep under the ground over short distances

Principal stress rotation under bidirectional simple shear loadings

Previous researches have indicated the non-coaxiality of sand in unidirectional simple shear tests, in which the direction of the principal axes of stresses does not coincide with the corresponding principal axes of strain rate tensors. Due to the limitation of apparatus that most of testing facilities can only add shear stress in one direction, the influence of stress history on the noncoaxiality of sand is not fully considered in previous tests. In this study, the effect of stress history on the non-coaxiality of sand is systematically studied by using the first commercially available Variable Direction Dynamic Cyclic Simple Shear system (VDDCSS). Samples of Leighton Buzzard sand (Fraction B) are first consolidated under a vertical confining stress and consolidation shear stress, and then sheared by a drained monotonic shear stress. Angle (θ) between the consolidation shear stress and the drained monotonic shear stress is varied from 0° to 180°, with an interval of 30°. The change of principal axes of stresses is predicted by well-established equations, and the principal axe of strain rate is calculated using recorded data. Results show that the level of non-coaxiality is increased by the increasing θ, especially at the initial stage of drained shearing

Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research